Herz-Kreislauf-Erkrankungen

Cardiovascular Diseases

Genmutationen verursachen Gefäßwandschäden und Herzschwäche

NGFN-Forscher fanden heraus, dass Mutationen in den Genen für Proteine der extrazellulären Matrix die Herzmuskelerkrankung verursachen. Die Mutationen bewirken bei den Betroffenen ein Absterben der Gefäßwandzellen und führen dadurch zu einer geschwächten Pumpfunktion des Herzens.

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Genetic Cause for Heart Attack Discovered

One in five Germans die of myocardial infarction, more commonly known as heart attack. NGFN scientists have played a decisive role in uncovering the genetic risk factors that lead to heart attack. Due to this discovery, doctors in the future will be able to better recognize and more quickly diagnose a heightened heart attack risk.

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27 genes offer a molecular diagnosis of heart failure

Scientists working with the NGFN have now succeeded, for the first time ever, in pinpointing which genes in particular are involved in the late stages of a specific cardiac muscle weakness known as dilatative cardiomyopathy.

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Heart Attack: Better Protection for High-Risk Patients

Heart Attack is the most frequent cause of death in Germany. It results from obstruction of the blood supply to the heart muscle („coronary artery disease“). NGFN-Scientists discovered that not only the risk but also the severity and course of coronary artery disease are under genetic control.

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Gene for heart Growth discovered

Symptoms of lovesickness in Zebrafish: the heart is badly damaged - it breaks. A gene-mutation is its cause. Dr. Wolfgang Rottbauer hopes to develop new drugs for heart attack patients by researching the genetic causes of cardiovascular diseases.

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